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β-amyloid peptide(Aβ)play a important role in pathologenesis of Alzheimer's disease (AD), This experiment study investigated the neurotoxic effects in ...展开
duced by Aβ and its possible mechanism by microinjecting the substance into hippocampal area of rats and exposing it to cultured neuronal cell from rats.In addition, the mechanism of the neuronal protection of melatonin via antioxidative way was presented in this study.It provide an experimental evidence for the understanding of the pathophysiological role in developmental AD, and for making the strategies in treatment of AD. 收起
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