说明:
The effective anticancer component, YT-11, salvaged and separated from traditional Chinese medicine produces a good curative effect on mice's liver ca ...展开
ncer, but the serious toxicity and excitement hinder this effective component from further study and development. In order to solve the problems such as some factors hindering YT-11 from going into the practical stage by methods in pharmaceutics, we used Butyl-α-cyanoacrylate (BCA) as carrier material which is safe, free from poison and side effects and biodegradable. We also studied systematically and comparatively the preparation technology, the forming of the preparation, the quality evaluation, the in vivo targeting character in mice and the original drug's pharmacology of YT-11's polybutylcyanoacrylate nanoparticles (YT-11-PBCA-NP). 收起